Membrane Proteins References

• Hilary term, second year: Prof Sansom's Membrane Channels lectures

• Hilary term, second year: Dr D Middleton's Biomembranes lectures.

• Hilary term, second year: The Membrane Proteins And Lipids practical.

• Trinity term, second year: Prof Sansom's Membrane Protein Structure lectures (revision notes available here).

• Past Finals questions.

Membrane Protein Structure

• Schulz, G, "Beta-barrel membrane proteins"; Current Opinion In Structural Biology 10(4), 443-447 (2000).

• Subramaniam, S, "The structure of bacteriorhodopsin: an emerging consensus"; Current Opinion In Structural Biology 9(4), 462-468 (1999).

• Wallin, E et al, "Genome-wide analysis of integral membrane proteins from eubacterial, archaen and eukaryotic organisms"; Protein Science 7(4), 1029-1038 (1998) (Abstract only unless you have subscription access).

• There is a webpage containing many example membrane protein structures here.

Receptor-Gated Ion Channels

• Miyazawa, A et al, "Nicotinic acetylcholine receptor at 4.6 angstrom resolution: Transverse tunnels in the channel wall"; Journal Of Molecular Biology 288(4), 765-786 (1999).

Voltage-Gated Ion Channels

• Biggin, P et al, "Potassium channel structure: domain by domain"; Current Opinion In Structual Biology 10(4), 456-461 (2000).

• Sansom, M, "Watching a voltage-sensor tilt and twist"; Current Biology 10(5), R206-R209 (2000).

Aquaporins

• Sansom and Law, "Membrane proteins: Aquaporins - channels without ions"; Current Biology 11, R71-R73 (2001).

• Borgnia, Nielsen, Engel and Agre, "Cellular and molecular biology of the aquaporin water channels"; Annu. Rev.Biochem. 68:425-458 (1999)

• Murata et al, "Structural determinants of water permeation through aquaporin-1"; Nature 407:559-605 (2000)

  Note: You will need a Nature subscription to access this paper.

• A primer on aquaporins in plants.

This page was written by Niall Harrison.