Nitric Oxide In Biology

• Hilary term, third year: Prof Ferguson's Nitric Oxide In Biology lecture (no entry in the course handbook).

General Reviews

• Mayer and Hemmens, "Biosynthesis and action of NO in mammalian cells"; Trends In Biochemical Sciences 22(12), 477-481 (1997)

• Ogden and Moore, "Inhibition of NO synthase - potential for a novel class of therapeutic agent?"; Trends In Biotechnology 13(2), 70-78 (1995).

• Colasanti, M, "The dual personality of NO"; Trends In Pharmacological Sciences 21, 249-252 (2000).

NO Synthase

• Stuehr, J, "Mammalian NO synthases"; Biochimica et Biophysica Acta - Bioenergetics 1411(2-3), 217-230 (1999).

• Groves, J, "NO synthase: models and mechanisms"; Current Opinion In Chemical Biology 4, 687-695 (2000).

The Activation Of Guanylate Cyclase

• Zhao et al, "A molecular basis for NO sensing by soluble guanylate cyclase"; PNAS 96(26), 14753-14758 (1999).

• Denninger and Marletta; "Guanylate cyclase and the NO/cGMP signalling pathway"; Biochimica et Biophysica Acta - Bioenergetics 1411(2-3), 334-350 (1999).

Haemoglobin As An NO Carrier

• Gross and Lane, "Physiological reactions of NO and Hb: A radical rethink"; PNAS 96(18), 9967-9969(1999).

• Durner et al, "Ancient origins of NO signaling in biological systems"; PNAS 96(25), 14206-14207 (1999).

NO And Mitochondrial Respiration

• Beltran et al, "The effect of NO on cell respiration: A key to understanding its role in cell survival or death"; PNAS 97(26), 14602-14607 (2000).

NO In The Brain

• Kiss And Sylvester, "NO: A novel link between synaptic and nonsynaptic transmission"; Trends In Neurosciences 24, 211-215 (2001).

This page was written by Niall Harrison.