Recombination Questions

1995

"Describe how you would distinguish recombination and complementation
experimentally and how in vitro complementation techniques expedite
purification of proteins without knowledge of their precise molecular
function."

"Compare the mechanisms of site-specific recombination and genetic
transposition.  Discuss critically the methods that have been used to
elucidate these mechanisms."

1996

"Compare the mechanisms of site-specific recombination and genetic
transposition.  Briefly outline the methods that have been used to
elucidate these mechanisms."

1997

"Write an essay on DNA damage, repair and mutation"

"Compare the mechanisms of site-specific recombination and genetic
transposition.  Outline how these processes are exploited in molecular
biology research."

1998

"Describe the phenomenon of gene conversion in yeast.  How does the
double-strand break model for recombination compare with the Holliday
model for recombination?"


1999
	
"Compare the mechanisms of genetic transposition, retroviral integration,
and immunoglobulin gene rearrangement.  Briefly indicate the experimental
approaches that have been used to elucidate these mechanisms."

2000

"Discuss how double-strand breaks in DNA arise and how they lead to the
process of homologous recombination.  Identify the key proteins that
participate in homologous recombination."