Post-Translational Modification References

• Hilary term, second year: Dr Rudd's Introduction To Glycobiology lectures.

• Past Finals questions.

General Glycosylation

• Shur, B, "The beginning of a sweet tale"; Current Biology 4(11), 996-999 (1994).

• Drickamer, K, "Evolving views of protein glycosylation"; Trends In Biochemial Sciences 23(9), 321-324 (1998).

• Dwek, R, "Toward understanding the function of sugars"; Chemical Reviews 96(2), 683-729 (1996).

• Here is some information about Glycoscience On The Internet.

Biosynthesis and Sequencing

• Takeda, J and Kinoshita, T; "GPI anchor biosynthesis"; Trends In Biochemical Sciences 20(9), 367-371 (1995).

• Kinarsky, L et al, "Structural analysis of peptide substrates for mucin-type O-glycosylation"; Biochemistry 37(37), 12811-12817 (1998).

• Rudd, P et al, "Oligosaccharide sequencing technology"; Nature 388, 205-207 (1997).

Immunological Glycosylation

• Jacob, G, "Glycosylation inhibitors in biology and medicine"; Current Opinion In Structural Biology 5(5), 605-611 (1995).

• Mattu, T et al, "The glycosylation and structure of human serum IgA1, Fab and Fc regions and the role of N-glycosylation on Fc receptor interactions"; Journal Of Biological Chemistry, 273, 2260-2272 (1998).

• Rudd, P et al, "The glycosylation of the complement regulatory protein, human erythrocyte CD59"; Journal Of Biological Chemistry, 272, 7229-7244 (1997).

• Rudd, P er al, "Roles for glycosylation of cell surface receptors involved in cellular immune recognition"; Journal Of Molecular Biology 293(2), 351-366 (1999).

Prion Protein Glycosylation

• Viles, J et al, "Copper binding to the prion protein: structural implications of four identical cooperative binding sites"; PNAS 96(5), 2042-2047 (1999).

• Rudd, P et al, "Glycosylation differences between the normal and pathogenic prion protein isoforms"; PNAS 96(23), 13044-13049 (1999).

Protein Folding

• Mehta, A et al, "Alpha-glucosidase inhibitors as potential broad-based anti-viral agents"; FEBS Letters 430(1-2), 17-22 (1998).

• Lewis, J and Elliott, T, "Evidence for successive peptide binding and quality control stages during MHC class I assembly"; Current Biology 8(12), 717-720 (1998).

This page was written by Niall Harrison.