Signalling Mechanisms References

• Hilary term, second year: Prof Armitage's Microbial Metabolism lectures.

• Past Finals questions (bacterial signalling).

• Past Finals questions (eukaryotic signalling).

Eukaryotic Signalling

Insulin Signalling

• Taha and Klip, "The insulin signalling pathway"; Journal Of Membrane Biology 169(1), 1-12 (1999).

• Ferrannini et al, "Insulin: New roles for an ancient hormone"; European Journal Of Clinical Investigation 29(10), 842-852 (1999).

• Holma and Kasuga, "From receptor to transporter: Insulin signalling to glucose transport"; Diabetologia 40(9), 991-1003 (1997).

• Nystrom and Quon, "Insulin signalling: Metabolic pathways and mechanisms for specificity"; Cellular Signalling 11(8), 563-574 (1999).

• Rameh and Cantley, "The role of PI3K lipid products in cell function"; Journal Of Biological Chemistry 274(13), 8347-8350 (1999).

• Sansom, C, "A future vaccine for diabetes?"; Drug Discovery Today 6, 332-333 (2001).

• Schmidt, Ann Marie, "A radical approach to the pathogenesis of diabetic complications"; Trends In Pharmacological Sciences 21, 367-369 (2000).

Bacterial Signalling

Two-Component Sensing

• Armitage et al, "Bacterial locomotion and signal transduction"; Journal Of Bacteriology 180(5), 1009-1022 (1998).

• Hoch, J, "Two-component and phospohrelay signal transduction"; Current Opinion In Microbiology 3, 165-170 (2000).

• Goudreau and Stock, "Signal transduction in bacteria: Molecular mechanisms of stimulus-response coupling"; Current Opinion In Microiology 1, 160-169 (1998).

Osmosensing

No online references that I know of. Feel free to fill me in if you know different...

Oxygen Sensing

• Unden and Schirawski, "The oxygen-responsive transcriptional regulator FNR of Escherichia coli: The search for signals and reactions"; Molecular Microbiology 25, 205-210.

• Ruby and McFall-Ngai, "Oxygen-utilising reactions and symbiotic colonisation of the squid light organ by Vibrio fischeri"; Trends In Microbiology 7(10), 414-420 (1999).

• Gregor and Klug, "Regulation of bacterial photosynthesis genes by oxygen and light"; FEMS letters 179(1), 1-9 (1999).

Quorum Sensing

• Fuqua et al, "Census and consensus in bacterial ecosystems: The LuxR-LuxI family of quorum-sensing transcriptional regulators"; Annual Reviews In Microbiology 50, 727-751 (1996).

• Ruby, E, "Lessons from a cooperative, bacterial-animal association: The Vibrio fischeri-Euprymna scolopes light organ symbiosis"; Annual Reviews In Microbiology 50, 591-624 (1996).

• Swift et al, "Quorum sensing: A population-density component in the determination of bacterial phenotype"; Trends In Biochemical Sciences 21(6), 214-219 (1996).

• Withers et al, "Quorum sensing as an integral component of gene regulatory networks in gram-negative bacteria"; Current Opinion In Microbiology 4, 186-193 (2001).

Virulence

• Cornelius and Wolf-Watz, "The Yersina Yop virulon: A bacterial system for subverting eukaryotic cells"; Molecular Microbiology 23, 861-867 (1997).

This page was written by Niall Harrison.