Death And Undeath References

• Past Finals Questions.

Apoptosis

• Raff, M, "Cell suicide for beginners"; Nature 396, 119-122 (1998).

• Various; "Nature Insight: Apoptosis"; Nature 407, 769-816 (2000) - a suite of papers on apoptosis, covering a range of aspects. The links takes you to an index of the other papers; the general review by Hengartner is especially recommended.

• Khwaja, A, "Apoptosis: Akt is more than just a Bad kinase"; Nature 401, 33-34 (401).

• Newton and Strasser, "The Bcl-2 family and cell death regulation"; Current Opinion In Genetics And Development 8(1), 68-75 (1998) (No PDF).

• Martins and Earnshaw, "Apoptosis: Alive and kicking in 1997"; Trends In Cell Biology 7(3), 111-114 (1997).

• Holcik, M, "Fatal embrace: Structural basis of caspase inhibition"; Trends In Genetics 17, 250 (2001).

• Los et al, "Caspases: More than just killers?"; Trends In Immunology 22, 31-34 (2001).

• Adams and Cory, "Life-or-death decisions by the Bcl-2 protein family"; Trends In Biochemical Sciences 26, 61-66 (2001).

• Grutter, M, "Caspases: key players in programmed cell death"; Current Opinion In Structural Biology 10, 649-655 (2000).

• Desagher et al, "Mitochondria as the central control point of apoptosis"; Trends In Cell Biology 10, 369-377 (2000).

• Bernadi et al, "A mitochondrial perspective on cell death"; Trends In Biochemical Sciences 26, 112-117 (2001).

• Inbal, B, et al, "DAP kinase links the control of apoptosis to metastasis"; Nature 390, 180-184 (1997).

• Li and Yuan, "Deciphering the pathways of life and death"; Current Opinion In Cell Biology 11, 261-266 (1999).

Cancer

• Various; "Nature Insight: Cancer"; Nature 411, 6835 (2001). Like the apoptosis Insight above, this is a suite of review articles highlighting recent developments in the field.

• McCormick, Frank, "Signalling networks that cause cancer"; Trends In Cell Biology 9, M53-M56 (1999).

• Keely et al, "Integrins and GTPases in tumour cell growth, motility and invasion"; Trends In Cell Biology 8(3), 101-107 (1998).

• Levitski, A, "Targeting signal transduction for disease therapy"; Current Opinion In Cell Biology 8(2), 239-244 (1996) (No PDF).

• Huang and Oliff, "Drug-targeting strategies in cancer therapy"; Current Opinion In Genetics And Development 11(1), 104-110 (2001).

• Jagus et al, "PKR, apoptosis, and cancer"; The International Journal Of Biochemistry And Cell Biology 31, 123-128 (1999).

Oncogenes

• Shields et al, "Understanding Ras: 'It ain't over 'til it's over'"; Trends In Cell Biology 10, 147-154 (2000).

• Kolibaba and Druker, "Protein tyrosine kinases and cancer"; BBA - Reviews On Cancer 1333, F217-F248 (1997).

• Seidensticker and Behrens, "Biochemical interactions in the wnt pathway"; BBA - Molecular Cell Research, 1495, 168-182 (2000).

Tumour Suppressor Genes

• Bartek et al, "The retinoblastoma protein pathway and the restriction point"; Current Opinion In Cell Biology 8(6), 805-814 (1996) (No PDF).

• Mittnacht, S, "Control of RB phosphorylation"; Current Opinion In Genetics And Development 8(1), 21-27 (1998).

• Hartmann et al, "The molecular epidemiology of P53 gene mutations in human breast cancer"; Trends In Genetics 13(1), 27-33 (1997).

• Vogelstein et al, "Surfing the p53 network"; Nature 408, 307-310 (2000).

• Lohrum and Vousden, "Regulation and function of the p53-related proteins: Same family, different rules"; Trends In Cell Biology 10, 197-202 (2000).

• Vidal and Koff, "Cell-cycle inhibitors: Three families united by a common cause"; Gene 247, 1-15 (2000).

• Macleod, Kay, "Tumour suppressor genes"; Current Opinion In Genetics And Development 10, 81-93 (2000).

This page was written by Niall Harrison.